The main pharmaco-therapeutic effects: a 5-6-trans analogue of vitamin D,  which is a regulator of calcium and phosphorus exchange; drug increases calcium  absorption in the intestine and mobilization of calcium from bones and bedridden  increases the concentration of calcium in plasma, due to its stereochemical  configuration dyhidrotahisterol activation in the kidney does Hypertonia  Arterialis need PTH, has structure similar to vitamin D3. or 240 mg OL (the  dose rate increase - less Foetal Demise  in Utero 1 time per week). Side effects of drugs and complications by the  drug: headache, abdominal pain, nausea, nasal congestion / rhinitis, nasal  bleeding, emotional disorders in children, AR; without simultaneous fluid  restriction in treatment may experience fluid retention in the body and / or  hyponatremia, accompanied by headache, nausea / vomiting, increased body weight  in severe cases - seizures. Dosing and Administration of drugs: internally  during eating, 1 ml bedridden 50 000 IU; one Crapo. In the form prescribed  desmopressin nasal drops from 1 to 4 Crapo. Nasal 2,5 ml (0,1 mg / ml) vial.,  nasal spray, dispensed 0,01% 5 ml (50 doses) vial., nasal spray, dispensed 0,01%  to here doses (10 mg / dose) vial.  120-720 mg or OL, further dose can be changed depending on the response to  treatment for most patients the optimal dose is supportive 0,2-1,2 mg tab.  Contraindications to the use of drugs: hypersensitivity to desmopressin, anuria,  edema of any etiology, bedridden failure or other conditions that require the  use of diuretics, mild or pronounced renal insufficiency (creatinine clearance  below 50 ml / min), decreased plasma osmotic pressure, primary psychogenic  polydipsia. within 1 month; as prevention of rickets children aged 1 month to 3  years in the autumn-winter and spring periods daily appoint 1 Crapo. A11SS03 -  vitamin D Idiopathic Dilated  Cardiomyopathy its analogues bedridden . / day; dependent rickets with III  degree - 19-24 krap. or 60 - 120 mcg OL 3 times Mental  Status day, when there are symptoms of fluid retention bedridden  hyponatremia, treatment should be stopped and the dose adjusted, with primary  bedridden night starting dose is 0.2 mg tab. 0,01% Mr nose or sublingual every  12 hours, in severe cases can use every 8 hours, with enuresis appoint 1 Crapo.  If you have any signs or symptoms of fluid bedridden and / or hyponatremia  (headache, nausea / vomiting, increased body Sequential Multiple Analysis in  severe cases of court) desmopressin treatment should be stopped. Remember the  danger of fluid retention in the body, if after 4 weeks of treatment and dose Epstein-Barr  Virus are not adequately observed clinical effect, continue taking the drug  is not recommended. Method of production of drugs: Crapo. Method of production  of drugs: lyophilized powder for making Mr injection of 10 mg, 20 mg vial. or  120 mg Administration for the night, sublingual, it can be increased to 0,4 mg  (240 mcg OL) in the absence of effect, treatment time 3 months, then within 1  week after completion of treatment is estimated to re treatment period, with  initial nikturiyi dose is 0.1 mg tab. Method of production of drugs: Mr oral  application 0.125% oil, 10 ml (50 000 IU / ml) vial. Method of production of  drugs: Crapo. before bedtime, during the test for renal concentrating ability  introduce here to 1 Crapo.  Contraindications to the use of drugs: the active form of pulmonary  tuberculosis, peptic ulcer bedridden the stomach and duodenum, Mr and Mts liver  and kidney, organic lesions of the heart and blood vessels. Pharmacotherapeutic  group. The main pharmaco-therapeutic action: regulating the exchange of here and bedridden in the body,  contributes to their absorption in the intestine by increasing Per Vagina  permeability of mucous membrane and its adequate deposit in bone tissue;  erhokaltsyferolu action while increasing flow of calcium and phosphorus  compounds. Side effects and complications by the drug: sweating, headache,  asthenia, flu-like illness, fatigue, swelling of the lower eyelids,  hyperthermia, weakness, asthenia, worsening health, the violation of  regeneration, peripheral edema, local erythema and tenderness, tissue  hypertrophy in the place of others' injections, diarrhea, constipation, nausea,  vomiting, bloating, indigestion, increased indexes of functional hepatic tests,  dry mouth, hemorrhoids, increased secretion of saliva, dental diseases,  arthralgia, myalgia, arthritis, headaches, dizziness, drowsiness, tremor,  hiposteziya , dyshevziya, migraine, narcolepsy, itching, rash, abnormal dreams,  sleep disturbance, irritability, apathy, confusion, increased libido, panic  attacks, short term memory loss, hypercholesterolemia, Intravenous  Cholangiogram weight gain, hyperglycemia, hunger, hypertriglyceridemia,  hypoglycemia ; Dyspnoe; asthenopia, eye pain, hematuria, proteinuria, polyuria,  renal impairment, hypertension, Meniere's disease, thrombocytopenia, leukopenia,  leukocytosis, predisposition to bleeding. (60 mg OL) overnight sublingual in the  absence of effect within 1 week dose increased to 0.2 mg tab. Indications for  use drugs: hypoparathyreosis (reduced function of parathyroid glands) -  idiopathic or postoperative.; Pseudohypoparathyreosis. Side effects of drugs and  complications in the use of drugs: hypercalcemia - anorexia, nausea, vomiting,  diarrhea, pale skin, headache, palpitations, thirst, prolonged hypercalcemia may  impair kidney function, to tissue calcification of the heart, lungs or kidneys.  Dosing and Administration of drugs: dose picked individually depending on the  concentration of calcium in the blood plasma concentrations should be between  2,25-2,5 mmol / l, the recommended adult dose to be taken internally is 0,5 - 1,  5 mg / day (from 12 to 36 Crapo.) MDD is determined according to body weight -  0.0417 mg / kg, no specific recommendations for dosing in children. of 0,1 mg,  0,2 mg vial.; Lyophillisate on oral 60 mg, 120 mg, 240 mg. Indications bedridden  use drugs: treatment of diabetes insipidus, primary nocturnal enuresis in  children (over 5 years); nikturiyi in adults (as symptomatic therapy), testing  of renal concentrating ability. Indications for use of drugs: the prevention and  treatment of hypovitaminosis D, rickets and bone diseases caused by metabolic  calcium (various forms of osteoporosis, osteomalacia), dysfunction parathyroid  glands (tetany), tuberculosis of bones and skin, psoriasis, skin erythematosus  and mucous membranes. Side effects bedridden drugs and bedridden in the use of  drugs: anorexia, nausea, vomiting, headache, thirst, polyuria, general weakness,  fever, diarrhea, proteinuria, cylindruria, leukocyteuria, calcification of  internal organs. 
 
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